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Why is my healthcare provider testing my neurotransmitters and hormones?

Improve Your Quality of Life

Data shows that neurotransmitter and hormone imbalances play an important role in the development of a variety of occasional symptoms that may impact your quality of life. However, the specific imbalances impacting your health often vary from person to person.

Your healthcare provider chose Sanesco's NeuroWellness Program for the insight it provides into the unique imbalances behind your occasional symptoms. With the information the test provides, your provider can safely and effectively restore neuroendocrine balance -- ultimately, improving your quality of life.

The partnership between your healthcare provider and Sanesco offers you an individualized approach through functional laboratory testing and product options.

Why are neurotransmitters and hormones important?

Neurotransmitters and hormones are the chemical messengers your body uses to communicate necessary changes throughout the body. Neurotransmitters send messages within the nervous system. Hormones send signals to tissues around the body.

Together, these chemicals control automatic functions ranging from breathing to blood flow to digestion. They also control your sleep, mood, mental function, and even how you respond to stress.

Neurotransmitters and hormones can become imbalanced after enduring stress. When imbalances are present, regulation of body functions breaks down, leading to symptoms.

What is my healthcare provider testing?

Your provider has chosen a profile to assess your specific health concerns. The neurotransmitters and hormones tested in our most popular profiles are listed below.

Other profiles are available. Basic versions do not include estrone and estriol.

HPA-G Complete

(Urine + Saliva)

Serotonin
GABA
Dopamine
Norepinephrine
Epinephrine
Glutamate
PEA

Cortisol x4
DHEA-S x2

Estrone
Estradiol
Estriol
Progesterone
Testosterone

HPA

(Urine + Saliva)

Serotonin
GABA
Dopamine
Norepinephrine
Epinephrine
Glutamate
PEA

Cortisol x4
DHEA-S x2

HP

(Urine only)

Serotonin
GABA
Dopamine
Norepinephrine
Epinephrine
Glutamate
PEA

Please remember it is important to ship your samples as quickly as possible!

What's Inside My Collection Kit?

Sample Collection

Depending on which test your healthcare provider chose, you will be collecting 1 urine sample and/or 4 saliva samples.

For Urine Collection:

  • 1 urine collection tube (white cap)
  • urine collection cup

For Saliva Collection:

  • 4 saliva collection tubes

Materials

There are two pieces to fill out and return with your specimens.

Patient Questionnaire
Allows your provider to make connections between your test results and symptoms to design your personalized health program.

Laboratory Requisition Form
Provides the technical information for processing your specimen and returning the test to your healthcare provider.

Shipping

Your kit includes a pre-paid shipping label. Place your samples in the biohazard bag. Remember to fill out and include the Requisition Form and Patient Questionnaire when shipping your samples.

You've got a Collection Kit, Now what?

There may be minor changes to collection materials over time to reduce waste and improve ease of use.
Please refer to ‘What’s Inside My Kit?’ above for an accurate list or contact us with questions.

What to expect after my healthcare provider gets my test results?

Once the test is complete, your personalized Correlation Analysis Report and Education (CARE) package will be sent to your healthcare provider. Your provider will contact you to discuss:

• The identified imbalances
• How imbalances connect with your symptoms
• Your personalized care program

Retesting- the Difference between Feeling Okay and Feeling Great

In order to achieve optimal health, and get their quickly, you need to check your progress. Retesting allows your healthcare provider to adjust your program, helping you save time and money in the long run.

The first retest is recommended at 9-12 weeks. This test checks to see how you are responding to interventions and determines if changes need to be made.

The second retest is recommended at about 6 months. This retest makes sure you have achieved balance.

Life is stressful, and stress can cause imbalances. Additional retesting may be performed annually to ensure life’s stressors haven’t derailed your progress.

Targeted Nutritional Formulas

Your healthcare provider may decide to use nutritional formulas as part of your care plan. Sanesco offers a specialty line of nutrition formulas specifically designed to target neurotransmitter and hormone imbalances.

Sanesco formulas are only available through your healthcare provider.

Frequently Asked Questions

Exercise that increases heart rate may affect catecholamines (hormones made by the adrenal glands) and maybe serotonin. Heavy exercise can lower Glutamate (an excitatory neurotransmitter in the brain involved in normal brain function) and GABA (a calming neurotransmitter). Heavy exercise will also induce a stress response, raising cortisol (a “stress hormone” produced by the adrenal gland).  This may affect your laboratory results.

Caffeine is a stimulant and will boost catecholamines and cortisol. This may then boost excitatory neurotransmitters and suppress inhibitory (Serotonin & GABA) function. Caffeine may also increase serotonin levels. This could affect your laboratory results.

Some medications or supplements may affect certain neurotransmitters. We ask that you list them on the questionnaire in case levels are too high or low. We also ask that you list approximately how long you have been taking them and what dosage you are taking.  Do NOT discontinue use of your medications without consultation with your healthcare provider.

Yes, you do not need to alter your normal routine. About 1 hour after rising is your first morning sample, no matter what hour the clock says.

Neurolab prefers that all samples are collected within the same day (24-hour period). However, if you are unable to collect all of your samples on the same day, there are two acceptable scenarios.

Scenario 1: If urine is collected on Day 1 and all 4 saliva samples are collected on Day 2, or vice versa, that will be fine.

Scenario 2: The patient attempts to collect the urine and 4 saliva samples throughout the course of one day.  The patient successfully collected the urine sample, but only collected 3 saliva samples and fell asleep before collecting their 4th saliva sample.  The 4th sample can be collected the following day but ONLY if it is collected at the same time of day that it should have been collected on the previous day.

Although it’s ideal to get all of your samples done in the same day, we will still accept your urine specimen on a different day that when you collected your 4 saliva samples. It should be collected as close as possible to the same date as the saliva samples were collected. Just make sure and note the date and time of the collection and label accordingly on the collection tube and questionnaire. *Note: Our laboratory will only accept samples that have been collected within 30 days. If you send in any samples that are more than 30 days old, we cannot process your results and we will inform your practitioner to recommend that you submit a new test.

Do NOT discontinue use of your medications or supplements without consultation with your healthcare provider. Neurolab does not require patients to refrain from taking any medications or supplements prior to collecting their samples.   Some medications or supplements may affect certain neurotransmitters. We ask that you list them on the questionnaire in case levels are too high or low. We also ask that you list approximately how long you have been taking them and what dosage you are taking.

Smelling a lemon traditionally is the most effective way to generate saliva. Saliva can also be collected by (pooling it) within the mouth for short periods to accumulate enough saliva for collecting a sample. Some patients have also reported success generating saliva by smelling/thinking about/cooking one of their favorite foods. When rinsing your mouth prior to each saliva collection, try using warm water rather than cold water.  Most importantly, relax.  You don’t have to fill the tube immediately. It may take some people longer than others to generate saliva.

Urine stabilizer looks like clear liquid droplets or condensation with a miniscule cotton ball inside of the urine tube.  Ensure the cotton ball is not stuck to the inner lid.  if it is, just shake it down before opening.  Since the urine collection requires mixing your sample with the stabilizer in the tube, you cannot rinse the urine tube or recollect a “mistake” urine sample by emptying the tube and recollecting in the same tube. Note: Saliva sample tubes (with colored caps) do not have a stabilizer and can be rinsed and re-used if necessary.

As long as the specimens have been frozen, you may go ahead and send in your specimens. If it has not been in the freezer, contact your healthcare provider for instructions on getting a new kit.  Ideally, it is best to submit the tests as close as possible to the sample collection date so that they don’t expire and you can obtain results faster.  We require you submit your samples no later than 30 days after you collect your sample.

The first morning urine is usually too concentrated for testing and will produce skewed results. By collecting your SECOND urine of the day (typically 2 to 3 hours after waking), we get a picture of both the inhibitory and excitatory systems as they get ready to meet the day.

Freezing is to control interfering bacteria. We recommend that you freeze each sample immediately upon collection and that you keep your specimens be frozen for at least 4 hours before sending them in. If necessary, you may leave your specimens in the freezer over night/weekend before sending them in.

They are good for up to 30 days in the freezer.

If you are taking the HPA-G, HPA or HP profile, the only thing expired in your kit is the urine tube. All you need is a replacement urine tube. The quickest way to get a replacement urine tube is directly from your healthcare provider. If that is not a valid option, you can call our customer support at: 866.670.5705 ext 2 and we can send a replacement urine tube directly to you.

We don’t suggest it.  Alcohol has dehydrating properties and can affect the results.  IF you choose to consume alcohol of any amount, please note it on the patient questionnaire.  Remember: Do not drink more than 8 oz of fluid prior to your urine collection, and do not drink anything (other than water) for at least one hour prior to each saliva collection.

For any sex hormone testing, if a transgender person has a menstrual cycle, collection should be on day 19, 20, or 21 of a normal 28-day cycle.

You should collect during the mid-luteal phase of your cycle. This is generally 7-9 days prior to menstruation.

If you are taking birth control pills, day 1 of your period would be day 1 of the active pills in your monthly birth control pack. Collect your samples on day 19, 20, or 21 of the active pills in the pack.